Immunology Multiple Choice Quiz on Antibodies

This immunology quiz is designed to assess your knowledge in ‘Antibodies’. Choose the best answer from the four options given. When you've finished answering as many of the questions as you can, scroll down to the bottom of the page and check your answers by clicking 'Score'. Percentage score will be displayed along with right answers.

1. The basic unit of immunoglobulin (Ig) is composed of:
Two identical heavy and two different light chains
Two different heavy and two different light chains
Two different heavy and two identical light chains
Two identical heavy and two identical light chains
2. IgE
is present in high concentration in serum
is bound together by J chain
bind to mast cells through its Fab region
differ from IgG antibody because of its different H chains
3. The Fab portions of Ig
contains the J chain
mediates biological effector functions of Ab molecules
binds to an Fc receptor
contains the idiotype of the Ig
4. Ig heavy chains are
not glycosylated
not important to binding of antigen
expressed by T cells
encoded by a constant region exon, variable exon, diversity exon and joining exon
5. IgA
crosses the placenta
is involved in hay fever
is present in saliva and milk
activates complement by the classical pathway
6. Human IgM
is largely restricted to the circulation
is the antibody produced by high affinity plasma cells
protects mucosal surfaces
crosses the placenta
7. The Fc region of antibody
generally confers biological activity on the various molecules
contains both heavy and light chains
is not important for triggering of IgE mediated hypersensitivity
is not a requirement for placental transmission
8. The Fab region of an Ig is responsible for:
C1q fixation
Binding to macrophages
Binding to antigen
Binding to Fc receptors
9. Cells destined to become IgA producing plasma cells do not
produce J Chain
produce secretory component
home to any mucosal area
migrate from mucosal areas on stimulation with antigen
10. Cleavage of IgG by Papain produces
Isolated heavy chains
Isolated light chains
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