DNA Damage and Repair Quiz || Molecular Biology Quiz

1.Bacteria produce an enzyme methylase, which mainly play a role in
Modification of DNA
Cutting of DNA
Repair of DNA
Rearrangement of DNA.

2.Methylation of Uracil forms which of the folllowing?
Adenine
Guanine
Cytosine
Thymine

3. Which of the following disease in humans is caused due to expanded microsatellite repeats?
Alkaptonuria
Cystic fibrosis
Tuberculosis
Huntington's disease

4. Which of the following enzyme is required for the photoreactivation of the DNA
DNA photoligase
DNA photolyase
AP endonuclease
DNA glycosylase

5.Which of the following is a heretitary disease associated with abnormal DNA repair
Haemophilia
Downs Syndrome
Blooms Syndrome
All of these

6. Deamination of which of the following bases will Not be recognised by the DNA damage repair machinery?
Adenine
Cytosine
S-Methyl Cytosine
Guanine

7. What is the main damaging effect of UV radiation on DNA?
Depurination
Formation of thymine dimers
Single strand break
None of these

8.A suitable example of DNA repair deficient disorder in human is
Sickle cell anemia
Albinism.
Xeroderma pigmentosum
Xeroderma pigmentosum and Albinism

9.Uvr ABC endonuclease is present in which repair system?
Mismatch repair
SOS repair
Base excision repair
Nucleotide Excision Repair

10. An enzyme that induces double strand breaks in DNA and rejoins them is called
DNA gyrase
DNA ligase
DNA polymerase
Restriction Endonuclease

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